金准生物，量子点，白介素6（IL-6）

[Product Name]IL-6 Detection Kit

[Sample Type]Serum, plasma, whole blood, or capillary blood

[Intended Use]
For the in vitro quantitative detection of Interleukin-6 (IL-6) in human serum, plasma, whole blood, or capillary blood.

[Clinical Department]
Clinical Laboratory, Outpatient & Emergency Department/ICU, Infectious Diseases Department, Respiratory Department, Paediatrics Department, Haematology Department, Rheumatology Department, etc.

Product Parameters
Item	IL-6
Test Time	18min
Sample Type	Serum, plasma, whole blood, or capillary blood
Sensitivity	0.002ng/ml
Storage Condition	4-30℃
Packing Specification	Card Type: 25 Tests/Kit, 50 Tests/Kit Cartridge type: 25 Tests/Kit, 50 Tests/Kit

1. Interleukin-6 (IL-6) is a sensitive marker for the early diagnosis of acute infection. It can act as a differential diagnostic indicator for early inflammation and early-stage sepsis, and bears significant reference value for formulating patient treatment regimens and improving clinical outcomes.

2. Elevated IL-6 levels are positively correlated with disease severity, with the magnitude of elevation reflecting the severity of the condition. In critically ill patients, IL-6 can maintain persistently high expression levels for an extended period. It serves as a sensitive indicator for assessing the severity and prognosis of patients with sepsis and Multiple Organ Dysfunction Syndrome (MODS), and can more rapidly reflect the efficacy of antibiotic therapy.

3. For inflammatory and infectious diseases, combined procalcitonin (PCT) and IL-6 testing not only enhances the early diagnostic rate of infection and prevents missed diagnoses, but also reduces misdiagnoses. It can be used as a sensitive dual-marker assay for the early warning and rapid diagnosis of sepsis, and effectively guides the rational administration of antibiotics. This is particularly critical for neonates, who present with acute onset, rapid disease progression and non-specific clinical manifestations—such cases are in greater need of this dual inflammatory marker assay (IL-6 + PCT). When PCT testing yields negative results while IL-6 testing is positive, a severe viral infection should be strongly suspected, and antibiotic administration is not recommended.

4. IL-6 levels are significantly elevated in stress responses such as autoimmune diseases, tumours, post-surgical states, burns and traumatic injuries, and exhibit a positive correlation trend with the severity of the corresponding conditions.

PCT/IL-6 Clinical Application
IL-6 (ng/mL)	Clinical Application Recommendations
<0.007	95th percentile reference value in apparently healthy individuals
0.007-0.150	Normal results may indicate the presence of mild inflammation or mild infection.
0.150-0.250	Suggests potential bacterial infection or systemic inflammatory response syndrome.
>0.250	Indicates a possible diagnosis of sepsis
*Each laboratory shall verify the applicability of the established reference ranges through internal validation studies; it is advisable to establish laboratory-specific reference ranges where necessary.

Number	Controls	Number of registration certificate
1	降钙素原质控品（Procalcitonin（PCT）Control）	粤械注准 20172400844
2	白介素6质控品（Interleukin-6（IL-6）Control）	粤械注准 20172400852
3	C反应蛋白质控品（C-Reactive Rrotein（CRP）Control）	粤械注准 20172400847
4	心肌肌钙蛋白 I 质控品（Cardiac Troponin I（cTnl）Control）	粤械注准 20172400846
5	肌酸激酶同工酶质控品（Creatine kinase Isoenzyme-MB（CK-MB）Control）	粤械注准 20172400849
6	D · 二聚体制控品（D-Dimer Control）	粤械注准 20172400843
7	人心型脂肪酸结合蛋白质控品（Human Heart-type Fatty Aeid Binding Rrotein（H-FABP）Control）	粤械注准 20172400851
8	肌红蛋白质控品（Myoglobin（MYO）Control）	粤械注准 20172400848
9	N末端脑钠肱前体质控品（N-terminal pro-B-type natriuretic peptide（NT-proBNP）Control）	粤械注准 20172400845
10	中性粒细胞明胶酶相关脂质运载蛋白质控品（Neutrophil gelatinase-assoiated lipocalin（NGAL）Control）	粤械注准 20172400850